My work at the University of Oxford focusses on isolating monoclonal antibodies from patients immunised with a novel vaccine against blood-stage malaria.
Methods: single memory B cell sorting, lysis and nested PCR amplification of paired immunoglobulin G heavy and light chains.
In the past, I have worked on the isolation and characterisation of monoclonal antibodies against Hepatitis C Virus and Human Immunodeficiency Virus.
University of Bari 1986 Manager of the Geriatrics Operating Unit 1992: Director of the School of Specialization in Geriatrics, until 2009 MAIN RESEARCH AREAS Lipoprotein metabolism, atherosclerosis, cardiology, brain aging, Alzheimer's disease and dementia, alimentation. Prof. Capurso founded and directed: 1. University Center for the Study of Lipoprotein Metabolism; 2. University Center for the Study of Cerebral Aging - Memory Research Unit For this research activity, he has been author and coauthor of numerous publications in national and international journals and has participated as a speaker at numerous national and international congresses .
Lewis Lanier, PhD, is chair and J. Michael Bishop MD Distinguished Professor of Microbiology and Immunology at UC San Francisco. Lanier has studied the immune systemâ€™s natural killer (NK) cells, a type of white blood cell that provides protection against microbial pathogens and tumors, for more than three decades. NK cells express a diverse array of inhibitory and activating receptors on their surface that bind to ligands expressed on the surface of potential target cells. His lab has identified and characterized many of these receptors, their ligands and associated signaling pathways, and has defined their role in innate and adaptive immune responses to pathogens and cancer. When NK cells encounter healthy cells, signals transmitted by inhibitory receptors dominate, preventing autoimmune responses. But the absence of ligands for inhibitory receptors or the upregulation of ligands for activating receptors in infected or malignant cells prompts NK cells to kill these abnormal cells and to secrete cytokines that induce a subsequent response by T-cells and B cells. Lanier hopes to apply this knowledge to the development of powerful NK cell-based cancer immunotherapies.
ryan R. Cullen obtained a B.Sc. in Biochemistry from Warwick University in the UK and a M.Sc. in Virology from the University of Birmingham before moving to the USA, where he obtained a Ph.D. in Microbiology from Rutgers University. In 1987, he was recruited to Duke University Medical Center as a Howard Hughes Medical Institute Investigator. He currently holds a James B. Duke Professorship in the Department of Molecular Genetics and Microbiology at Duke. Dr. Cullenâ€™s research interests have historically revolved around the use of viruses as genetic tools to understand aspects of the biology of the eukaryotic cell, focusing particularly on RNA-sequence mediated gene regulation. Currently, his laboratory is studying the regulation of viral mRNA expression by epitranscriptomic modifications and the use of CRISPR/Cas as a potential approach to the treatment of chronic diseases caused by DNA viruses. Dr. Cullen has published over 315 research papers, is on the editorial board of 11 prominent journals and has been recognized as one of the most highly cited scientists in the field of microbiology.
Professor Paolo Vineis is Chair of Environmental Epidemiology at Imperial College, London.He is Head of the Unit of Genetic and Molecular Epidemiology at the HuGeF Foundation, Torino, Italy.Paolo Vineis is a leading researcher in the fields of molecular epidemiology and exposomics
Gordon Life Science Institute
H-index -> 147
Gordon Life Science Institute
H-index -> 147
Dr. Kuo-Chen Chou is the founder of Gordon Life Science Institute, the first Internet Research Institute ever established in the world. He is also a Distinguished High Impact Professor and Advisory Professor of several Universities. As of May 2019, Professor Chou has published over 600papers with H-index over147according to Google Scholar Citations. He has been named by Thompson Reuters/Clarivate Analytics as a Highly Cited Researcher in 2014, 2015, 2016, 2017, and 2018, listed in the â€œWorldâ€™s Most Influential Mindsâ€. In 2017, he has been selected by Web of Science and Clarivate Analytics as one of the 21 â€œBrightest Starsâ€ in science. For more information about him, visit a Wikipedia article at https://en.wikipedia.org/wiki/Kuo-Chen_Chou, and for more information for his publications, visit his web-page at http://gordonlifescience.org/.